H35. 3233 became effective on October 1, 2023. 3 Although an estimated 80% of. Randomized trial of treat-and-extend versus monthly dosing for neovascular age-related macular degeneration: 2-year results of the TREX-AMD study. Choroidal neovascularization (CNV) is part of the spectrum of exudative age-related macular degeneration (AMD) that consists of an abnormal growth of vessels from the choroidal vasculature to the neurosensory retina through the Bruch's membrane. These blood vessels grow in an area called the choroid. Short description: Other vascular disorders of iris and ciliary body, unsp eye The 2024 edition of ICD-10-CM H21. . The 2024 edition of ICD-10-CM H21. Wet or neovascular AMD (nAMD) is characterised by choroidal neovascularization (CNV), resulting in macular haemorrhage, effusion and fibrosis . The ICD-10 codes for age-related macular degeneration (AMD) involve both laterality and staging. 121 became effective on October 1, 2023. The 2024 edition of ICD-10-CM H35. 3211: 362. 059: Retinal neovascularization: H35. AMD is classified as either dry or wet (neovascular), and dry AMD may manifest as early, intermediate, or advanced disease. 1 cm/cm 1. As there are no ICD-10 codes specific for AMD or its type (neovascular or dry), we considered as AMD patients those submitted to one of the two procedures in the public system exclusively available for AMD patients . Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in people over the age of 50 worldwide. Neovascular age-related macular degeneration (AMD) is the leading cause of irreversible blindness in elderly population. Wet (exudative) AMD, with inactive choroidal. Age-related macular degeneration is a potentially progressive maculopathy. 50 is a billable medical code that can be used to indicate a diagnosis on a reimbursement claim, however, 362. 2024 (effective 10/1/2023): No change. The following code(s) above H30. Dry (nonexudative or atrophic): All age-related macular degeneration (AMD) starts as the dry form. During the past 15 years, new treatment paradigms for neovascular age-related macular degeneration (nvAMD) have evolved due to the advent of intravitreal anti-vascular endothelial growth factor. Background. 309 may differ. AMD is classified into two forms, a non-neovascular or “dry” form and a neovascular or “wet” form (Fig. ICD-10-CM; H35. 3231. Purpose: To describe the clinical and multimodal imaging (MMI) features of age-related macular degeneration (AMD) eyes presenting with intraretinal exudation and no evidence of neovascularization or structural alterations of native retinal vessels. The 2024 edition of ICD-10-CM H35. Wet AMD. Symptoms reported on the date of nAMD diagnosis, if any, were also recorded and assigned to one of three categories: decreased vision, visual distortion/metamorphopsia, or report of a scotoma. The frequency of intravitreal injections has significantly increased since the introduction of anti-vascular endothelial growth factor. 329 - other international versions of ICD-10 E11. 4% of patients 65 to 74 years old and 19. 323 contain annotation back-references that may be applicable to H35. Although these lesions were not associated with a significant decrease in visual acuity, the presence of nonexudative MNV seems to be an important predictor of exudative disease. 32 coding with all applicable Excludes 1 and Excludes 2 notes from the section level conveniently shown with each code. 1 became effective on October 1, 2023. The 2024 edition of ICD-10-CM D22. 1122 became effective on October 1, 2023. 311-E08. Neovascular glaucoma is an aggressive form of secondary glaucoma. Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in people over the age of 50 worldwide. 52 - Exudative macular degen: Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code. 051 may differ. Q. 3) or a claim for intravitreal injection [Classification Commune des Actes Médicaux (CCAM) procedure code BGLB001] (Figure 1, Step 1). The ocular blood supply has been implicated in. 3211 H35. 323 may differ. by 2050. The AMD population is expected to be 288 million by 2040 [3, 4]. After a vitrectomy is performed, the Epi-Rad90 Ophthalmic System delivers beta radiation (strontium 90) directly to the area of the retina affected by wet ARMD. 3233 - other international versions of ICD-10 H35. The most robust clinical trial data in this area are derived from the ARED trials ( 13, 27 ). 32xx) as follows: In the right eye, 1 The left eye, 2 For bilateral, 3Neovascular age-related macular degeneration (AMD) is an advanced form of AMD that can cause rapid and severe vision loss. 90 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. AMD, and especially nAMD, is the main cause of visual impairment and blindness in developed countries [Citation 2, Citation 5,. 1. 1% (5 of 441) in patients from the control arms. H35. 4, 5 Although neovascular AMD (nAMD) can be successfully treated with VEGF inhibitors, the treatment of GA remains a substantially. POHS is asymptomatic until choroidal neovascularization (CNV) or sequelae such as disciform. 31x4 for advanced atrophic dry. The overall prevalence is approximately 8. Pathological or degenerative myopia refers to a spherical equivalent of -8. H33. CNV is diagnosed by an eye specialist, an ophthalmologist, who. Macular Telangiectasia. 351 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. 31x3 for advanced atrophic dry AMD without subfoveal involvement— geographic atrophy (GA) not involving the center of the fovea. This is the American ICD-10-CM version of H35. 329 became effective on October 1, 2023. Although neovascular AMD (nAMD) accounts for only 10% of AMD patients, the majority of severe vision loss associated with AMD is due to nAMD. 311 - other international versions of ICD-10 H35. AMD is classified as either dry or wet (neovascular), and dry AMD may manifest as early, intermediate, or advanced disease. 3223 became effective on October 1, 2023. Due to an aging population, the global prevalence of AMD is projected to rise from 170 to 288 million by the year 2040 []. 52X0 contain annotation back-referencesPolypoidal choroidal vasculopathy (PCV) is a disease of the choroidal vasculature. Patients who present with submacular hemorrhage often have profound vision loss, which can be permanent owing to the toxic effects of heme on the photoreceptors and retinal pigment epithelium. H35. 11). ↓ See below for any exclusions,. Although 85% of AMD is dry, 80 to 90% of severe vision loss caused by AMD results from the wet type. The 2024 edition of ICD-10-CM H16. 3290 may differ. and neovascularisation. Age-related macular degeneration (AMD) is a leading cause of visual impairment and blindness in people older than 50 years. Subscribe to Codify by AAPC and get the code details in a flash. Search All ICD-10; ICD-10-CM Diagnosis Codes; ICD-10-PCS Procedure Codes; ICD-10-CM Diagnosis Index; ICD-10-CM External Causes Index; ICD-10-CM Table of Drugs; ICD-10-CM Table of Neoplasms; HCPCS Codes; ICD-9-CM Diagnosis Codes; ICD-9-Vol-3 Procedure Code; Search All DataH34. Age-related macular degeneration (AMD) constitutes a prevalent, chronic, and progressive retinal degenerative disease of the macula that affects elderly. Ophthalmologists at UC Davis Health used an experimental gene therapy last month to treat a patient with wet age-related macular degeneration, or wet AMD. The bottom line: While PCV presents similarly to wet AMD, an early differential diagnosis can save vision. ” The “angle” referred to here is the angle between the iris, which makes up the colored part of your eye, and. As mentioned above, patients with neovascular AMD and larger. -) New blood vessels originating from the corneal veins and extending from the limbus into the adjacent corneal stroma. In the wet form, rapid, severe vision loss can occur due to the development of. Short description: Retinal neovascular NOS. 3210 - H35. Choroidal neovascularization (CNV) is the medical term for growth of new blood vessels beneath the eye’s retina (subretinal). Parent Code Notes: H35. It is estimated that 6. By Lee Vien, OD, and David Yang, OD. According to thorough estimates, 200 million people worldwide are estimated to have AMD, and by 2040, this number is projected to rise to close to 300 million. ICD-10-CM Coding Rules. The 2024 edition of ICD-10-CM H16. The eye's drainage angle between the iris and cornea controls the flow of aqueous humor (clear fluid of the eye). It’s caused by the growth of abnormal blood vessels between the iris and the cornea. 3220 may differ. ICD-10-CM Diagnosis Codes that Support Coverage Criteria ICD-10-CM Code Description H35. ICD-10-CM Coding Rules. 29 - other international versions of ICD-10 C96. Key: Red numerals (6th position) indicate laterality; green numerals (7th position) indicate staging. 059: Retinal neovascularization, unspecified [associated with age-related macular degeneration] H35. Age-related macular degeneration (AMD) is one of the most common causes of severe vision loss in the developed world. Excludes2: diabetic retinal disorders (E08. The following code (s) above H35. g. Age-related macular degeneration (AMD) is the leading cause of severe vision loss in individuals over the age of 50 years. ICD-10 codes covered if selection criteria are met: H35. Abstract. 50 became effective on October 1, 2023. 1 may differ. The ICD-10 codes for age-related macular degeneration (AMD) involve both laterality and staging. 31xx), and wet AMD (H35. 3291 for Exudative age-related macular degeneration, unspecified eye, with active choroidal neovascularization is a medical classification as listed by WHO under the range - Diseases of the eye and. This is the American ICD-10-CM version of H35. Answer: According to Gordon Johns, MD, author of ICD-10-CM for Ophthalmology, either code is appropriate. Prior treatments. 3223 contain annotation back-references. Billable/Specific Code. In industrialized countries, age-related macular degeneration (AMD) is a leading cause of blindness in adults older than 60 years of age. 1 Severe vision loss from GA is less common than from. In AMD patients, Yannuzzi found an incidence of 4% of non-vascularized PED among serous PED (15). 5 kg/m 2 1. 22 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The first major change in ICD-10-CM codes for 2017 is for diabetic ocular complication coding. Thirty-two eyes of 32 patients with nAMD were included in this prospective, observational study. 32 may differ. 4 may differ. 1 Introduction. Currently, the approved. 6%) of the population aged 40 years and older in. This is the American ICD-10-CM version of H26. 212 may differ. doi: 10. 3131 contain annotation back-references. This is the American ICD-10-CM version of H02. This review aims to provide a comprehensive guide to the pathophysiology, clinical and imaging characteristics, natural course and treatment of the. Showing 1-25: ICD-10-CM Diagnosis Code H44. Early AMD. 0): 124 Other disorders of the eye with mcc or thrombolytic agent. 3211 for Exudative age-related macular degeneration, right eye, with active choroidal neovascularization is a medical classification as listed by WHO under the range - Diseases of the eye and adnexa . 5% in patients older than 75. It is found in the 2024 version of the ICD-10 Clinical Modification (CM) and can be used in all HIPAA-covered transactions from Oct 01, 2023 - Sep 30, 2024. ICD-10 code H35. 1. 052 became effective on October 1, 2023. Presumed ocular histoplasmosis syndrome (POHS) occurs secondary to infection with the yeast form of Histoplasma capsulatum. 25 to 27% AMD in the fellow eyes of patients with unilateral exudative AMD. Put the anti-VEGF medicine into your eye with a very small needle. Cystoid macular degeneration, unspecified eye. The following code(s) above H34. 311 may differ. H35. Among eyes with at least 20/40 VA at baseline, 81% maintained 20/40 VA when wet AMD disease activity was detected by ForeseeHome or routine/symptom-based eye examination (Figure 2). 7. Advanced forms of AMD are seen in primarily 2 types, exudative AMD involving the presence of choroidal neovascularization and nonexudative or dry AMD. population in persons older than 65 years, as well as the most common cause of blindness in the Western world. brookss. diagnosis of neovascular AMD (ICD-9-CM code 362. 1). ]. 3290 contain annotation back-references. 50 should only be used for claims with a date of service on or before September 30, 2015. 1 Polypoidal choroidal vasculopathy (PCV), which presents as a serosanguinous maculopathy, is a variant of neovascular AMD. ICD-10-CM Coding Rules. The Epi-Rad90 Ophthalmic System™ (NeoVista, Inc. Convert H35. wet AMD mean? All patients with AMD begin with the non-neovascular, or dry, form. With PCV, “there’s leaking under the retina, macular edema, intraretinal edema, subretinal hemorrhage, and detachment, so it looks like typical exudative AMD until you do more specific testing,” said Dr. The retina is a layer of neurosensory tissue in the eye that converts light into neural signals that the brain interprets as images. INTERMEDIATE AMD DEFINED. 1 Any stage of dry AMD can turn into wet AMD, which typically causes faster vision loss. 16 should only be used for claims with a date of service on or before September 30, 2015. ,. 059 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. 3) or a claim for intravitreal injection [Classification Commune des Actes Médicaux (CCAM) procedure code BGLB001] (Figure 1, Step 1). This is the American ICD-10-CM version of H35. ICD-10 codes covered if selection criteria are met: H35. the advanced form of non-neovascular AMD, will have one or more zones of well- demarcated retinal pigment epithelial and/or. The 2024 edition of ICD-10-CM D31. It represents approximately 10% of all AMD cases. Age-related macular degeneration (AMD) is a progressive, degenerative disease of the human retina which in its most aggressive form is associated with the formation of macular neovascularization (MNV) and subretinal fibrosis leading to irreversible blindness. Retinal neovascularization, unspecified, left eye. 4 may differ. H35. 342 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. 50 may differ. 8111 contain annotation back-references. ICD-10-CM Code for Exudative age-related macular degeneration, right eye, with active choroidal neovascularization H35. Neovascular AMD (nAMD) represents a small subset (less than 10%) of total AMD cases; however, the neovascular form is responsible for the majority of cases of severe visual loss in eyes with AMD . 3210 - other international versions of ICD-10 H35. Introduction. Correct staging enables more accurate characterization, which is important for understanding risk for visual loss; it also helps to ensure accurate documentation and efficient billing. 219 - other international versions of ICD-10 H26. This decreased significantly, with 24 of the eyes. 3233 became effective on October 1, 2023. 10), and risk of late AMD among female non-smokers with increased with BMI (HR per 2. When originally published, dry AMD — regardless of which eye — was coded as H35. H40-H42. Rubeosis iridis. Age related macular degeneration (AMD) is the most common cause of vision loss in the elderly population. H35. 3 Although an estimated 80% of. Neovascular AMD comprises 10% of all cases and can lead to devastating visual loss due to choroidal neovascularization (CNV). 2. 1X9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2024 edition of ICD-10-CM H35. H35. 351 - other international versions of ICD-10 H35. 89 - other international versions of ICD-10 H25. Article CAS Google Scholar500 results found. 3223. 22 may differ. 3213 is a valid billable ICD-10 diagnosis code for Exudative age-related macular degeneration, right eye, with inactive scar . The conversion to wet AMD can occur at any stage of dry AMD, but is more likely in. 1 PCNMs account for 10% of all choroidal neovascular membranes with a female predilection. The introduction of intravitreal anti-VEGF in clinical practice has played a key role in the management of exudative neovascular AMD and has led to improved overall visual prognosis. This is the American ICD-10-CM version of D22. H 35. Eyes with both CD and RPD appear to have very thin SFCT. Annual Meeting News. Exudative macular degeneration is the wet form of AMD, a leading cause of vision loss in people over 55. Referred to retina for same day evaluation and aflibercept injections. The 2024 edition of ICD-10-CM C96. (AMD), chronic central serous retinopathy (CSR). The following code(s) above E11. Wet AMD was coded as H35. SIERRA-AMD: a retrospective, real-world evidence study of patients with neovascular age-related macular degeneration in the. [2] Around 30% of these patients also develop myopic CNVM in the fellow eye as well. However H40. 3131 - other international versions of ICD-10 H35. Age related macular degeneration (AMD) is the most common cause of vision loss in the elderly population. 1 percent) that presented with CNV demonstrated progressive macular atrophy during an average follow-up of 11. Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. Of all "pseudomelanomas" (entities that mimic melanoma), this. Introduction. Of 51 patients with MNV in the contralateral eye, 23 eyes, 10 eyes, 12 eyes, and 6 eyes showed neovascular AMD, polypoidal choroidal vasculopathy, retinal angiomatous proliferation (RAP), and. 5 letters in the T&E arm and 9. 30: Unspecified macular degeneration [age-related] H35. New vessels associated with serous PED are represented in. There are various cytokine pathways involved in the formation and leakage from CNV. 121 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. This is the American ICD-10-CM version of H33. Characterized by drusen formation, macular pigmentary changes, geographic atrophy, and neovascularization of the choriocapillaris with exudation. 50 became effective on October 1, 2023. 1. H35. 89 became effective on October 1, 2023. injury (trauma) of eye and orbit ( S05. Short description: Exudative age-rel mclr degn, left eye, with inactive scar The 2024 edition of ICD-10-CM H35. The. 1-5 In 2010, 2. Approximately 10-15% of the cases of macular degeneration are the “wet” (exudative) type. Wet (exudative) AMD, with active choroidal neovascularization H35. No ICD-10 codes exist specifically for Retinal Pigment Epithelial Tears. ICD 10 code for Nonexudative age-related macular degeneration,. 11948. 2A9 may differ. This is the American ICD-10-CM version of H16. Learn about the causes, symptoms, treatment, and prevention of neovascular glaucoma. 819 - other international versions of ICD-10 H43. In the United States, AMD occurs in 10% of the population aged between 65 and 74 years and in 25% of population with more than 74 years. Your eye doctor will then use a special. Retinal angiomatous proliferation (RAP) is a subtype of neovascular age-related macular degeneration (AMD), which is one of the leading causes of blindness in elderly people in developed countries. 1 may differ. Retinal pigment epithelial detachment (PED) is defined as a separation of the retinal pigment epithelium (RPE) from the inner collagenous layer of Bruch’s membrane. In clinical trials, use of SYFOVRE was associated with increased rates of neovascular (wet) AMD or choroidal neovascularization (12% when administered monthly, 7% when. This is the American ICD-10-CM version of D31. Jul 10, 2018. 7%, although it varies significantly among different populations. Over 8 million people are affected worldwide with GA, approximately 20% of all individuals with AMD. Thread Link: Neovascular ARMD icd 10. 329 contain annotation back-referencesThe prevalence of subclinical nonexudative neovascular AMD in the fellow eyes of patients with unilateral exudative AMD ranged from 6. 9 - other international versions of ICD-10 M31. If a person has AMD, yellow waste protein deposits called drusen build up under the retina. 32x Exudative age-related macular degeneration Reviews, Revisions, and Approvals Date Approval Date Policy adopted from Health Net NMP283 Neovascular (Wet) Macular Degeneration Treatment 11/16 Reviewed – no changes 11/17 11/17Summary. Patients with neovascular AMD in one eye have a 4 – 12% per year cumulative risk of developing neovascular AMD in the fellow eye. A case of idiopathic choroidal neovascular membrane (CNVM) is described in a 17-year-old female patient. Peripapillary choroidal neovascular membranes (PCNM) were first described in 1928 by Lopez and Green. 2A9 became effective on October 1, 2023. 1 million adults age 50 years and older in the US had AMD. 342 became effective on October 1, 2023. 3290 - other international versions of ICD-10 H35. In 10 – 15% of patients with dry AMD, the disease converts to the wet form, which is also an advanced form of AMD. You’ll get eye drops to widen (dilate) your pupils. 90 contain. The management of neovascular age-related macular degeneration (nAMD) has taken a major stride forward with the advent of anti-VEGF agents. 9 : M00-M99. 32x Exudative age-related macular degeneration Reviews, Revisions, and Approvals Date Approval Date Policy adopted from Health Net NMP283 Neovascular (Wet) Macular Degeneration Treatment 11/16 Reviewed – no changes 11/17 11/17 Summary. It is the policy of Health Net of California that ocular photodynamic therapy (PDT) is medically necessary for the treatment of neovascular AMD with predominately. The 2024 edition of ICD-10-CM D22. 4%. which accounts to approximately 24% of newly diagnosed exudative AMD (17). (ICD-10) code H35. The 2024 edition of ICD-10-CM D31. 3 mg or 0. 329 may differ. Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness for Americans aged 65 years and older according to the Centers for Disease Control and Prevention. In contrast, AMD-associated CNV lesions are typically larger, are often associated with hemorrhage and drusen, and may be accompanied by sub-RPE fluid. 30: Unspecified macular degeneration [age-related] H35. H16. Subjects with AMD were identified using the International Classification of Diseases, Tenth Revision (ICD‐10), code for AMD (H353) by an ophthalmologist within a year before the health screening examination. H35. 81% having the atrophic form in at least one eye, but increases to 3. Evidence supports that symptomatic patients with PCV can have. The prevalence of GA goes up with age and it is slightly less than that of neovascular AMD. Source ICD-10-CM Code Target ICD-9-CM Code; H35. While PPCNVM, associated with optic nerve head drusen. 351 may differ. -) 124 Other disorders of the eye with mcc or thrombolytic agent. Dry age-related macular degeneration (dAMD) is a chronic eye disease that can impair vision and progress to severe central vision loss []. It can generally be classified as occult (type 1) or classic (type 2). H35. Download PDF. Short description: Exdtve age-rel mclr degn, left eye, with actv chrdl neovas The 2024 edition of ICD-10-CM H35. Applicable To. When you get this treatment, your doctor will: Put numbing medicine in your eye. 403 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. MeSH. 89 to ICD-9-CM. ICD-10-CM/PCS MS-DRG v38. Top. doi: 10. 1 million adults age 50 years and older in the US had AMD. Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in people over the age of 50 worldwide []. Age-related macular degeneration (AMD) has been described as the leading cause of legal blindness, affecting 10%–13% of adults over 65 years of age in North America, Europe, Australia and, recently, Asia. The prognosis for exudative AMD is significantly worse when compared with nonexudative AMD. 3221 for Exudative age-related macular degeneration, left eye, with active choroidal neovascularization is a medical classification as listed by WHO under the. By 2040, AMD is projected to affect nearly 288 million people worldwide (95% CI, 205–399) []. H35. Key Points. 8121 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. 142 may differ. Focal choroidal excavation (FCE) is a newly recognized clinical entity that is often incidentally found, and presents asymptomatic or with mildly decreased visual acuity in the affected eye. 3390/ijms21218242. It is interesting that one study noted increased choriocapillaris non-perfusion compared to fellow non-neovascular eyes, implying that choriocapillaris ischemia may play a critical role in the development of these lesions. -) Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes. 0 or less or an axial length of 32. There is no proven treatment to halt the progression of this degeneration. 1,2,11 The Beaver Dam Eye Study examined the incidence of disease in a cohort of patients aged. 059: Retinal neovascularization, unspecified [associated with age-related macular degeneration] H35. Age-related macular degeneration (AMD) is the leading cause of blindness in people over 50 years of age, accounting for 8. CLINICAL CLUES. Neovascular age-related macular degeneration (nAMD) is a common world-wide cause of visual loss. 3110, H35. Anti-VEGF injections usually only work for a short time, so most. H35. 3290 is applicable to adult patients aged 15 - 124 years inclusive. 32 Exudative age-related macular degeneration Wet age-related macular. 89. ICD - 9. ICD 10 code for Exudative age-related macular degeneration, bilateral, with active choroidal. Age-related macular degeneration (AMD) is a leading cause of visual impairment and blindness in people older than 50 years. This is the American ICD-10-CM version of H26. In the 2021 study, median VA was 20/25-2 among eyes with a known baseline. 3210 contain annotation back-references. The following code (s) above D31. This is the American ICD-10-CM version of H35. H35. To study associations of optical coherence tomography (OCT) features with presenting visual acuity (VA) in treatment naive neovascular age-related macular degeneration (nAMD). H00-H59 Diseases of the eye and adnexa H35 Other retinal disorders Approximate Synonyms Age related macular degeneration, nonexudative Age-related nonexudative macular degeneration of left eye Age-related nonexudative macular degeneration of right eye Bilateral age-related nonexudative macular degeneration H35. 25% to 27%. Fundus photo and fluorescein angiogram of a classic choroidal neovascular membrane in exudative age-related macular degeneration. H00-H59 Diseases of the eye and adnexa H35 Other retinal disorders Approximate Synonyms Age related macular degeneration, nonexudative Age-related. Age-related macular degeneration (AMD) is the main cause of blindness in the developed world in subjects aged ≥55 years, mainly with risk factors and genetic predisposition, with the number of patients affected being counted in millions and likely to increase with the population longevity.